Using the Brooks Men's Adrenaline GTS 22 is easy. Just slip them on and start your road running. They're designed to keep you in your natural stride and offer a comfortable running experience. When it comes to care, it's a good idea to keep them clean. You can use a soft brush and mild soap to gently clean the mesh and other parts of the shoes. Let them air dry; avoid using a dryer as high heat can damage the materials. Also, be careful not to expose them to sharp objects that could tear the mesh. For best performance, replace the shoes when you notice significant wear on the soles or loss of cushioning.