These Brooks Women's Glycerin 20 running shoes are great for road running. To use them, simply lace them up tight enough to support your feet but not too tight to cause discomfort. When running, you'll feel the soft cushioning which makes each step smooth. As for maintenance, after each run, let them air dry if they get wet. Don't put them in a dryer as it might damage the materials. Regularly check the soles for wear and tear. If you notice significant wear, it might be time to replace them. Also, store them in a cool, dry place when not in use to keep them in good condition.